A research team from Utrecht University has successfully fabricated working livers using a newly developed ultrafast volumetric 3D bioprinting method. By means of visible light tomography, the volumetric bioprinting method enabled the successful printing of miniature stem cell units by making the cells “transparent”, which meant they retained their resolution and ability to perform biological processes. Printed in less than 20 seconds, the liver units were able to perform key toxin elimination processes mimicking those that natural livers perform in our bodies, and could open new opportunities for regenerative medicine and personalized drug testing. Volumetric bioprinting of liver-like metabolic biofactories. Image via Advanced Materials. Ultrafast volumetric 3D bioprinting The Utrecht team first demonstrated their volumetric bioprinting technique in 2019 with the creation of free-form tissue structures. The method differs from current bioprinting processes which are based on layer-by-layer deposition and assembly of repetitive building blocks, such as cell-laden hydrogels and… read more